High anti-HLA response in women exposed to intrauterine transfusions for severe alloimmune hemolytic disease is associated with mother-child HLA triplet mismatches, high anti-D titer, and new red blood cell antibody formation
Transfusion 2013;53(5):939-947
Verduin EP, Schonewille H, Brand A, Haasnoot GW, Claas FH, Lindenburg IT, Lopriore E, Oepkes D, Roelen DL, Doxiadis II
co-author, author 6 of 10·doi·pubmed
Summary
Women whose fetus received intrauterine transfusions form HLA antibodies more often than blood donors with children who were never transfused. The study maps the factors involved, including the degree of HLA mismatch between mother and child.
Summary based on the published abstract.
- Type
- Immunological study
- Role
- Co-author, author 6 of 10
- Subjects
- haemolytic disease of the fetus and newborn
- PMID
- 22924899
citeVerduin EP, Schonewille H, Brand A, Haasnoot GW, Claas FH, Lindenburg IT, Lopriore E, Oepkes D, Roelen DL, Doxiadis II. High anti-HLA response in women exposed to intrauterine transfusions for severe alloimmune hemolytic disease is associated with mother-child HLA triplet mismatches, high anti-D titer, and new red blood cell antibody formation. Transfusion. 2013;53(5):939-947. doi:10.1111/j.1537-2995.2012.03862.x